Do not try to lose weight too rapidly. Crash diets and diet pills that promise weight loss are usually bad for you and actually don't help keep the weight off in the long run. Resist the urge to take the "easy" way out and instead stick with a healthier lifestyle. This way you lose the weight and improve your health, helping you keep the weight off in a way that won't harm you in the long run.
In a way, moderate-intensity physical activity is that "magic pill" a lot of people are looking for, because the health benefits go beyond keeping your waistline trim: Not only can it reduce your risk of cancer, stroke, diabetes and heart attacks, but studies have shown that physical activity can significantly improve the moods of patients with major depressive disorders.